Description

(4-(Cyclopropylcarbamoyl)-2-Fluorophenyl)Boronic Acid is a high-purity, advanced pharmaceutical intermediate featuring a boronic acid functional group critical for modern synthetic methodologies. This compound matters as a key building block in the synthesis of complex molecules, particularly in medicinal chemistry for the development of novel therapeutics. It is primarily needed by R&D scientists and process chemists in the pharmaceutical, agrochemical, and fine chemical industries engaged in Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting kinase inhibition.
• Suzuki-Miyaura Cross-Coupling Reagent: Serves as a versatile boronic acid coupling partner for forming carbon-carbon bonds with aryl or vinyl halides, a cornerstone reaction in modern organic synthesis.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Synthesis: Employed in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science: Potential building block for creating organic electronic materials and advanced polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and scale-up services for client projects.

Basic Information

Product Name	(4-(Cyclopropylcarbamoyl)-2-Fluorophenyl)Boronic Acid
CAS No.	874289-37-9
Molecular Formula	C10H11BFNO3
Molecular Weight	222.01 g/mol
Synonyms	2-Fluoro-4-(N-cyclopropylcarbamoyl)phenylboronic Acid; [4-(Cyclopropylaminocarbonyl)-2-fluorophenyl]boronic Acid; B-[4-(Cyclopropylcarbamoyl)-2-fluorophenyl]boronic Acid; 4-Cyclopropylcarbamoyl-2-fluorobenzeneboronic Acid; (4-Cyclopropylcarbamoyl-2-fluorophenyl)boronic Acid; 874289-37-9; 2-Fluoro-4-(cyclopropylcarbamoyl)benzeneboronic Acid
EINECS	Contact for details

Quality Control

Our (4-(Cyclopropylcarbamoyl)-2-Fluorophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards required for cGMP and ISO-certified environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.