Description

4-tert-Butylcarbamoyl-2-Fluorobenzeneboronic Acid, 97% is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in its dual functional groups, enabling its use as a key intermediate in the synthesis of complex organic molecules, particularly through cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid coupling partner for constructing biaryl and heterobiaryl structures, which are common motifs in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorinated aromatic structure for enhanced biological activity and stability.
• Material Science: Employed in the creation of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology & Proteomics: Acts as a valuable tool compound for bioconjugation and the development of chemical probes to study biological processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	4-tert-Butylcarbamoyl-2-Fluorobenzeneboronic Acid, 97%
CAS No.	874289-35-7
Molecular Formula	C11H15BFNO3
Molecular Weight	239.06 g/mol
Synonyms	2-Fluoro-4-[(tert-butylamino)carbonyl]benzeneboronic Acid; 4-(tert-Butylcarbamoyl)-2-fluorophenylboronic Acid; 2-Fluoro-4-(N-tert-butylcarbamoyl)phenylboronic Acid; 4-(tert-Butylaminocarbonyl)-2-fluorobenzeneboronic Acid; 2-Fluoro-4-(tert-butylcarbamoyl)benzeneboronic Acid; B-[4-[(1,1-Dimethylethyl)amino]carbonyl]-2-fluorophenyl]boronic Acid; 874289-35-7
EINECS	Contact for details

Quality Control

Our 4-tert-Butylcarbamoyl-2-Fluorobenzeneboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure the specified purity of 97% (min) and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	97% min
Water Content (KF)	< 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.