Description

Dimethyl 4-Borono-3-Fluorobenzamide is a high-purity, functionalized benzamide derivative containing both boronic acid and fluorine substituents. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: The boronic acid functional group makes it an essential reagent for forming carbon-carbon bonds in complex molecule assembly.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Serves as a precursor for advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or linker in bioconjugation and target identification studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research and scale-up projects.

Basic Information

Product Name	Dimethyl 4-Borono-3-Fluorobenzamide
CAS No.	874289-30-2
Molecular Formula	C9H11BFNO3
Molecular Weight	210.99 g/mol
Synonyms	4-Borono-3-fluoro-N,N-dimethylbenzamide; 3-Fluoro-4-(dimethylcarbamoyl)benzeneboronic acid; (3-Fluoro-4-(dimethylcarbamoyl)phenyl)boronic acid; 4-(Dimethylcarbamoyl)-2-fluorophenylboronic acid; B-[3-Fluoro-4-(dimethylaminocarbonyl)phenyl]boronic acid; 874289-30-2; 4-Borono-3-fluorobenzamide, N,N-dimethyl-
EINECS	Contact for details

Quality Control

Our Dimethyl 4-Borono-3-Fluorobenzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.