Description

2-Fluoro-4-(n-Ethylaminocarbonyl)Phenylboronic Acid is a specialized organoboron compound that serves as a crucial building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a fluorinated aromatic ring and an amide moiety, enabling the construction of complex, pharmaceutically relevant molecules. This high-purity intermediate is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling, particularly for compounds containing fluorinated aromatic systems.
• Agrochemical Research: Used in the discovery and development of novel herbicides, fungicides, and insecticides that require specific fluorinated structural motifs.
• Material Science: Serves as a monomer or precursor for creating advanced polymers and organic electronic materials with tailored properties.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents targeting serine hydrolases and other enzymes.
• Ligand Synthesis: Precursor for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D programs.

Basic Information

Product Name	2-Fluoro-4-(n-Ethylaminocarbonyl)Phenylboronic Acid
CAS No.	874289-29-9
Molecular Formula	C9H11BFNO3
Molecular Weight	210.99 g/mol
Synonyms	2-Fluoro-4-(N-ethylcarbamoyl)phenylboronic acid; (2-Fluoro-4-[(ethylamino)carbonyl]phenyl)boronic acid; 4-Carbamoyl-2-fluorophenylboronic acid, N-ethyl-; B-[2-Fluoro-4-[(ethylamino)carbonyl]phenyl]boronic acid; 874289-29-9; 2-Fluoro-4-(ethylaminocarbonyl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(n-Ethylaminocarbonyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.