Description

4-Cyclohexylcarbamoyl-2-Fluorobenzeneboronic Acid, 97% is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a key intermediate for constructing complex molecules via cross-coupling reactions, particularly the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, as well as in advanced materials science for creating novel functional polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and protein-protein interactions.
• Suzuki-Miyaura Cross-Coupling: Primarily utilized as a versatile boronic acid coupling partner for forming carbon-carbon bonds with aryl or vinyl halides, enabling the construction of complex biaryl structures.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) engaged in methodological development and discovery chemistry.

Basic Information

Item	Detail
Product Name	4-Cyclohexylcarbamoyl-2-Fluorobenzeneboronic Acid, 97%
CAS No.	874289-27-7
Molecular Formula	C₁₃H₁₇BFNO₃
Molecular Weight	265.09 g/mol
Synonyms	2-Fluoro-4-(cyclohexylcarbamoyl)benzeneboronic Acid; (2-Fluoro-4-((cyclohexylamino)carbonyl)phenyl)boronic Acid; 4-(Cyclohexylaminocarbonyl)-2-fluorobenzeneboronic Acid; 2-Fluoro-4-(N-cyclohexylcarbamoyl)phenylboronic Acid; 4-Carbamoyl-2-fluorobenzeneboronic Acid Cyclohexylamide; B-[2-Fluoro-4-[(cyclohexylamino)carbonyl]phenyl]boronic Acid; CAS 874289-27-7
EINECS	Contact for details

Quality Control

Our 4-Cyclohexylcarbamoyl-2-Fluorobenzeneboronic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure the specified purity of 97% (min.) and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance in research and pre-clinical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	97% min.
Water Content (KF)	< 1.0%
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.