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2-Fluoro-4-(1-Pyrrolidinylcarbonyl)Benzeneboronic Acid, 97% CAS NO 874289-25-5
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CAS No.:874289-25-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Fluoro-4-(1-Pyrrolidinylcarbonyl)Benzeneboronic Acid, 97% is a high-purity boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients and advanced materials.
Application
- Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
- Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, enabling the creation of compounds with specific biological activity.
- Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as polymers for OLEDs or sensors.
- Chemical Biology Probes: Employed in the creation of bioconjugates and molecular probes for studying biological processes and target engagement.
- Cross-Coupling Reactions: A specialized reagent for Suzuki-Miyaura cross-coupling, facilitating the formation of carbon-carbon bonds between aromatic rings under mild conditions.
- Library Synthesis: Valuable for combinatorial chemistry and high-throughput screening libraries in drug discovery efforts.
Basic Information
| Product Name | 2-Fluoro-4-(1-Pyrrolidinylcarbonyl)Benzeneboronic Acid, 97% |
| CAS No. | 874289-25-5 |
| Molecular Formula | C11H13BFNO3 |
| Molecular Weight | 237.04 g/mol |
| Synonyms | 2-Fluoro-4-(pyrrolidine-1-carbonyl)phenylboronic Acid; [2-Fluoro-4-(1-pyrrolidinylcarbonyl)phenyl]boronic Acid; 4-Borono-3-fluoro-N-pyrrolidylbenzamide; 2-Fluoro-4-(N-pyrrolidylcarboxamido)benzeneboronic Acid; 874289-25-5; B-[2-Fluoro-4-(1-pyrrolidinylcarbonyl)phenyl]boronic Acid |
| EINECS | Contact for details |
Quality Control
Our 2-Fluoro-4-(1-Pyrrolidinylcarbonyl)Benzeneboronic Acid, 97% is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity confirmation and NMR for structural verification, to ensure it meets the specified 97% minimum purity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research and production requirements.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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