Description

4-(n-Methylaminocarbonyl)-2-Fluorophenylboronic Acid is a specialized organoboron compound featuring a fluorinated aromatic ring and a methylaminocarbonyl substituent. This unique structure makes it a valuable high-purity building block for advanced chemical synthesis, particularly in cross-coupling reactions. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex biaryl structures found in drug candidates.
• Agrochemical Research: Used in the development of new herbicides and pesticides that require fluorinated aromatic components.
• Material Science: Serves as a monomer or functionalization agent in the synthesis of advanced polymers and organic electronic materials.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create fluorinated probes and tags for studying biological systems and protein interactions.
• Custom Synthesis: A critical starting material for contract research organizations (CROs) and CDMOs producing bespoke fine chemicals.

Basic Information

Product Name	4-(n-Methylaminocarbonyl)-2-Fluorophenylboronic Acid
CAS No.	874289-23-3
Molecular Formula	C9H11BFNO3
Molecular Weight	210.99 g/mol
Synonyms	2-Fluoro-4-[(methylamino)carbonyl]benzeneboronic Acid; 4-(Methylcarbamoyl)-2-fluorophenylboronic Acid; (2-Fluoro-4-(methylcarbamoyl)phenyl)boronic Acid; 2-Fluoro-4-(N-methylaminocarbonyl)phenylboronic Acid; B-[2-Fluoro-4-[(methylamino)carbonyl]phenyl]boronic Acid; 874289-23-3; 4-Carbamoyl-2-fluorophenylboronic Acid N-methyl derivative
EINECS	Contact for details

Quality Control

Our 4-(n-Methylaminocarbonyl)-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.