Description

4-(Cyclopropylcarbamoyl)-3-Fluorophenylboronic Acid is a specialized organoboron compound featuring a cyclopropylamide and a boronic acid functional group on a fluorinated aromatic ring. This unique structure makes it a valuable high-purity building block for modern synthetic chemistry, particularly in cross-coupling reactions. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures found in drug candidates.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides that require the cyclopropyl and fluorophenyl motifs.
• Material Science: Serves as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology: Employed in the synthesis of probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring complex boronic acid derivatives.

Basic Information

Product Name	4-(Cyclopropylcarbamoyl)-3-Fluorophenylboronic Acid
CAS No.	874289-20-0
Molecular Formula	C10H11BFNO3
Molecular Weight	223.01 g/mol
Synonyms	3-Fluoro-4-(N-cyclopropylcarbamoyl)phenylboronic Acid; [3-Fluoro-4-(cyclopropylcarbamoyl)phenyl]boronic Acid; 4-(Cyclopropylaminocarbonyl)-3-fluorobenzeneboronic Acid; B-[4-(Cyclopropylcarbamoyl)-3-fluorophenyl]boronic Acid; 3-Fluoro-N-cyclopropyl-4-boronobenzamide; 874289-20-0; FChem; AKOS; Ambeed
EINECS	Contact for details

Quality Control

Our 4-(Cyclopropylcarbamoyl)-3-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and pre-clinical standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.