Description

4-(tert-Butylcarbamoyl)-3-Fluorobenzeneboronic Acid is a high-purity (98%) boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a protected amide moiety, enabling precise molecular construction. This advanced intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for creating complex fluorinated aromatic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates containing fluorinated aromatic systems and amide linkages.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for constructing biaryl and heterobiaryl structures central to many drug molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluorobenzene scaffold is prevalent.
• Material Science: Employed in the creation of organic electronic materials, ligands for catalysts, and advanced polymers.
• Chemical Biology & Proteomics: Can be utilized in the design of molecular probes and enzyme inhibitors due to its specific reactive handles.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-(tert-Butylcarbamoyl)-3-Fluorobenzeneboronic Acid
CAS No.	874289-18-6
Molecular Formula	C11H15BFNO3
Molecular Weight	239.06 g/mol
Synonyms	[4-[(tert-Butylamino)carbonyl]-3-fluorophenyl]boronic acid; 3-Fluoro-4-[(2-methylpropan-2-yl)carbamoyl]benzeneboronic acid; 4-(N-tert-Butylcarbamoyl)-3-fluorobenzeneboronic acid; 3-Fluoro-4-(tert-butylcarbamoyl)phenylboronic acid; B-[4-[(1,1-Dimethylethyl)amino]carbonyl]-3-fluorophenyl]boronic acid; 874289-18-6; 4-(tert-Butylcarbamoyl)-3-fluorophenylboronic acid
EINECS	Contact for details

Quality Control

Our 4-(tert-Butylcarbamoyl)-3-Fluorobenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure a consistent purity of 98% (minimum) and confirm structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.