Description

4-(Butylcarbamoyl)-3-Fluorobenzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides by constructing fluorinated aromatic scaffolds.
• Material Science: Serves as a monomer or building block for synthesizing advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: A versatile reagent for constructing biaryl and heterobiaryl compounds in medicinal chemistry and discovery libraries.
• Fluorine Chemistry: The fluorine substituent makes it valuable for developing compounds with enhanced metabolic stability, bioavailability, and binding affinity.
• Laboratory Reagent: Used in academic and industrial R&D for method development and exploring new synthetic pathways.

Basic Information

Item	Details
Product Name	4-(Butylcarbamoyl)-3-Fluorobenzeneboronic Acid
CAS No.	874289-17-5
Molecular Formula	C11H15BFNO3
Molecular Weight	239.06 g/mol
Synonyms	3-Fluoro-4-(butylcarbamoyl)benzeneboronic Acid; 4-(N-Butylaminocarbonyl)-3-fluorobenzeneboronic Acid; [3-Fluoro-4-(butylcarbamoyl)phenyl]boronic Acid; B-[4-[(Butylamino)carbonyl]-3-fluorophenyl]boronic Acid; 874289-17-5; 4-Butylcarbamoyl-3-fluorophenylboronic Acid; 3-Fluoro-4-(butylcarbamoyl)phenylboronic acid
EINECS	Contact for details

Quality Control

Our 4-(Butylcarbamoyl)-3-Fluorobenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure a typical purity of ≥98% and conformity to specifications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided to guarantee traceability and reliable performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect purity and reactivity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.