Description

3-Fluoro-4-(Isopropylcarbamoyl)Benzeneboronic Acid is a high-value boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its core value lies in its dual functionality, combining a reactive boronic acid group for Suzuki-Miyaura cross-coupling reactions with a fluorinated aromatic amide moiety, enabling precise molecular construction. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for creating complex, fluorinated biaryl structures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or cross-linking agent in the creation of advanced polymers and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: The boronic acid functionality makes it a premier reagent for forming carbon-carbon bonds between aromatic rings under mild conditions.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes and diagnostic agents for biological target identification.
• Ligand Synthesis: Acts as a precursor for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Fluoro-4-(Isopropylcarbamoyl)Benzeneboronic Acid
CAS No.	874289-16-4
Molecular Formula	C10H13BFNO3
Molecular Weight	225.03 g/mol
Synonyms	[3-Fluoro-4-(isopropylcarbamoyl)phenyl]boronic acid; (3-Fluoro-4-((isopropylamino)carbonyl)phenyl)boronic acid; 4-Borono-2-fluoro-N-isopropylbenzamide; 2-Fluoro-4-boronobenzoic acid isopropylamide; B-[3-Fluoro-4-[(1-methylethyl)aminocarbonyl]phenyl]boronic acid; 874289-16-4; 3-Fluoro-4-(isopropylaminocarbonyl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Isopropylcarbamoyl)Benzeneboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.