Description

3-Fluoro-4-(Propylcarbamoyl)Benzeneboronic Acid is a specialized organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a fluoro-substituted aromatic carboxamide moiety, enabling precise molecular construction. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Research: Used in constructing novel herbicide and fungicide molecules, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Material Science: Building block for creating functionalized polymers, liquid crystals, and organic electronic materials through palladium-catalyzed cross-coupling.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of enzyme inhibitors or molecular probes.
• Academic & Contract Research: Enables methodological development and discovery chemistry in university and CRO (Contract Research Organization) laboratories worldwide.

Basic Information

Product Name	3-Fluoro-4-(Propylcarbamoyl)Benzeneboronic Acid
CAS No.	874289-15-3
Molecular Formula	C10H13BFNO3
Molecular Weight	225.03 g/mol
Synonyms	[3-Fluoro-4-(propylcarbamoyl)phenyl]boronic acid; (3-Fluoro-4-propylcarbamoylphenyl)boronic acid; 4-Borono-2-fluoro-N-propylbenzamide; 2-Fluoro-4-boronobenzoic acid propylamide; B-[3-Fluoro-4-[(propylamino)carbonyl]phenyl]boronic acid; 874289-15-3; Boronic acid, B-[3-fluoro-4-[(propylamino)carbonyl]phenyl]-; 3-Fluoro-4-propylaminocarbonylbenzeneboronic acid
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-4-(Propylcarbamoyl)Benzeneboronic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical R&D and scale-up processes. Each lot is fully characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting regulatory filings and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.