Description

3-Fluoro-4-(Pyrrolidine-1-Carbonyl)Phenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functional groups, enabling it to act as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides by constructing complex aromatic scaffolds.
• Material Science: Building block for organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the development of chemical probes and inhibitors for studying enzyme function and protein-protein interactions.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: A valuable reagent for method development and discovery chemistry in academic and contract research organizations (CROs).

Basic Information

Product Name	3-Fluoro-4-(Pyrrolidine-1-Carbonyl)Phenylboronic Acid
CAS No.	874289-09-5
Molecular Formula	C11H13BFNO3
Molecular Weight	237.04 g/mol
Synonyms	[3-Fluoro-4-(pyrrolidine-1-carbonyl)phenyl]boronic acid; (3-Fluoro-4-(pyrrolidine-1-carbonyl)phenyl)boronic acid; 4-Borono-2-fluoro-N-pyrrolidylbenzamide; B-[3-Fluoro-4-(1-pyrrolidinylcarbonyl)phenyl]boronic acid; 3-Fluoro-4-(1-pyrrolidinylcarbonyl)benzeneboronic acid; 874289-09-5; AKOS025244065
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-4-(Pyrrolidine-1-Carbonyl)Phenylboronic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.