Description

4-Carbamoyl-3-Fluorophenylboronic Acid is a high-purity, functionalized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in enabling precise cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Used as a versatile boronic acid partner for forming carbon-carbon bonds in medicinal chemistry and material science research.
• Agrochemical Synthesis: Employed in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organoboron catalysts.
• OLED and Electronic Material Research: Used in the synthesis of fluorinated organic semiconductors and light-emitting materials.
• Chemical Biology Probes: Facilitates the creation of tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	4-Carbamoyl-3-Fluorophenylboronic Acid
CAS No.	874288-39-8
Molecular Formula	C7H7BFNO3
Molecular Weight	182.95 g/mol
Synonyms	3-Fluoro-4-carbamoylphenylboronic Acid; (3-Fluoro-4-carbamoylphenyl)boronic Acid; 4-Borono-2-fluorobenzamide; 2-Fluoro-4-boronobenzamide; B-(3-Fluoro-4-carbamoylphenyl)boronic Acid; 3-Fluoro-4-aminocarbonylphenylboronic Acid; 874288-39-8; AKOS BRN-0768
EINECS	Contact for details

Quality Control

Our 4-Carbamoyl-3-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.