Description

4-(3-Fluorophenylcarbamoyl)Phenylboronic Acid is a specialized organoboron compound featuring both a boronic acid functional group and a fluorinated amide linker. This molecular architecture makes it a valuable high-purity building block for advanced synthesis, particularly in the development of complex pharmaceutical intermediates and functional materials. It is primarily needed by research institutions and fine chemical manufacturers engaged in Suzuki-Miyaura cross-coupling reactions and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those targeting specific receptors where the fluorophenyl moiety is critical.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for creating biaryl and heterobiaryl structures, a fundamental reaction in modern organic and medicinal chemistry.
• Material Science Research: Used in the development of organic electronic materials, polymers, and metal-organic frameworks (MOFs) where its structural motifs can impart specific electronic or binding properties.
• Agrochemical Synthesis: Employed in the research and development of novel herbicides, fungicides, and plant growth regulators that incorporate fluorinated aromatic systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.

Basic Information

Item	Detail
Product Name	4-(3-Fluorophenylcarbamoyl)Phenylboronic Acid
CAS No.	874288-05-8
Molecular Formula	C13H11BFNO3
Molecular Weight	259.04 g/mol
Synonyms	[4-(3-Fluorophenylaminocarbonyl)phenyl]boronic acid; 4-Carbamoylphenylboronic acid 3-fluoroanilide; 3-Fluoro-N-[4-(dihydroxyboranyl)benzoyl]aniline; 4-(3-Fluorophenylcarbamoyl)benzeneboronic acid; B-[4-[(3-Fluorophenyl)carbamoyl]phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our 4-(3-Fluorophenylcarbamoyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and elemental analysis to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.