Description

2-Chloro-3-Fluorobenzyl Bromide is a versatile and high-purity halogenated benzyl bromide intermediate essential for advanced organic synthesis. This compound matters for its role as a critical building block in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for introducing the benzyl bromide moiety into complex molecular architectures.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized monomers or additives for advanced polymers and specialty materials.
• Chemical Biology Probes: Useful for the preparation of molecular probes and tags for studying biological systems and mechanisms.

Basic Information

Product Name	2-Chloro-3-Fluorobenzyl Bromide
CAS No.	874285-19-5
Molecular Formula	C7H5BrClF
Molecular Weight	223.47 g/mol
Synonyms	1-(Bromomethyl)-2-chloro-3-fluorobenzene; (2-Chloro-3-fluorophenyl)methyl Bromide; α-Bromo-2-chloro-3-fluorotoluene; 2-Chloro-3-fluoro-α-bromotoluene; 2-Chloro-3-fluorobenzylbromide; 2-Chloro-3-fluoro-benzyl bromide; Benzene, 1-(bromomethyl)-2-chloro-3-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Fluorobenzyl Bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); ensure containers are kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.