Description

Ethanone, 2,2-Difluoro-1-(3-Thienyl)- is a high-purity fluorinated thiophene derivative, identified by CAS No. 874279-92-2. This compound serves as a critical advanced intermediate in the synthesis of complex organic molecules, valued for its unique difluoroacetyl moiety attached to a thiophene ring. It is primarily sought after by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical sectors for constructing novel active ingredients.

Application

• Key fluorinated building block in pharmaceutical research for the development of new drug candidates.
• Advanced intermediate in the synthesis of agrochemicals, including herbicides and fungicides.
• Precursor for materials science applications, particularly in the development of specialty polymers and electronic chemicals.
• Versatile reagent in organic synthesis for introducing the 2,2-difluoro-1-(3-thienyl)ethyl fragment.
• Used in academic and industrial R&D for exploring structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Product Name	Ethanone, 2,2-Difluoro-1-(3-Thienyl)-
CAS No.	874279-92-2
Molecular Formula	C6H4F2OS
Molecular Weight	162.16 g/mol
Synonyms	2,2-Difluoro-1-(thiophen-3-yl)ethan-1-one; 3-(2,2-Difluoroacetyl)thiophene; 1-(3-Thienyl)-2,2-difluoroethanone; 2,2-Difluoro-1-(3-thienyl)ethanone; 3-Acetylthiophene, 2,2-difluoro-; Thiophene-3-yl difluoromethyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2-Difluoro-1-(3-Thienyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.