Description

5-Carboxy-2-Fluorophenylboronic Acid is a multifunctional boronic acid derivative that serves as a key synthetic intermediate in modern organic chemistry. Its value lies in the unique combination of a reactive boronic acid group for Suzuki-Miyaura cross-coupling and a carboxylic acid moiety for further derivatization, enabling the construction of complex fluorinated aromatic structures. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Critical building block for synthesizing fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides with fluorinated aromatic cores.
• Material Science: Serves as a monomer or precursor for creating fluorinated polymers and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design of boronic acid-based probes, sensors, and inhibitors for studying biological processes.
• Ligand Synthesis: Useful for preparing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Research: A valuable starting material for custom synthesis houses and CROs (Contract Research Organizations) serving the life sciences sector.

Basic Information

Product Name	5-Carboxy-2-Fluorophenylboronic Acid
CAS No.	874219-59-7
Molecular Formula	C7H6BFO4
Molecular Weight	183.93 g/mol
Synonyms	2-Fluoro-5-carboxyphenylboronic Acid; (5-Carboxy-2-fluorophenyl)boronic Acid; 5-Carboxy-2-fluorobenzeneboronic Acid; B-(5-Carboxy-2-fluorophenyl)boronic Acid; 2-Fluorobenzene-1,4-dicarboxylic Acid (boronic acid derivative); 874219-59-7; FCBA
EINECS	Contact for details

Quality Control

Every batch of 5-Carboxy-2-Fluorophenylboronic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.