Description

trans-4-Aminocyclohexanecarbonitrile is a versatile chiral amine building block with a rigid cyclohexane backbone and a nitrile functional group. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical industries. It is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), fine chemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, including kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides with improved efficacy and selectivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals and dyes.
• Material Science Research: Investigated as a monomer or modifying agent for polymers and advanced organic materials.
• Chemical Biology & Proteomics: Utilized as a building block for activity-based probes and molecular tags.

Basic Information

Product Name	trans-4-Aminocyclohexanecarbonitrile
CAS No.	873651-89-9
Molecular Formula	C7H12N2
Molecular Weight	124.18 g/mol
Synonyms	trans-4-Aminocyclohexanecarbonitrile; (1r,4r)-4-Aminocyclohexanecarbonitrile; 4-Aminocyclohexanecarbonitrile (trans-); 4-Cyano-cyclohexylamine (trans-); trans-4-Cyano-cyclohexylamine; 4-Amino-trans-cyclohexanecarbonitrile; (trans)-4-Aminocyclohexanecarbonitrile; 873651-89-9
EINECS	Contact for details

Quality Control

Our trans-4-Aminocyclohexanecarbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.