Description

3-Amino-4-Fluorophenylboronic Acid is a multifunctional aromatic boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, combining an amino group, a fluorine atom, and a boronic acid moiety, makes it a versatile intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for applications in Suzuki-Miyaura cross-coupling reactions and the development of bioactive compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorine-containing drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the fluorine atom enhances biological activity and environmental stability.
• Suzuki-Miyaura Cross-Coupling: A vital boron reagent for palladium-catalyzed carbon-carbon bond formation, enabling the construction of complex biaryl structures in medicinal and materials chemistry.
• Materials Science Research: Building block for creating novel organic electronic materials, sensors, and metal-organic frameworks (MOFs) due to its functional handle for further modification.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and affinity ligands for studying protein interactions and enzyme activity.
• Ligand Synthesis for Catalysis: Serves as a starting material for preparing specialized bidentate or tridentate ligands used in homogeneous catalysis.

Basic Information

Product Name	3-Amino-4-Fluorophenylboronic Acid
CAS No.	873566-75-7
Molecular Formula	C6H7BFNO2
Molecular Weight	154.94 g/mol
Synonyms	(3-Amino-4-fluorophenyl)boronic acid; 4-Fluoro-3-aminophenylboronic acid; 3-Amino-4-fluorobenzeneboronic acid; B-(3-Amino-4-fluorophenyl)boronic acid; 3-Amino-4-fluorophenyl-B(OH)2; 873566-75-7; AFAB; 4-Fluoro-m-aminophenylboronic Acid
EINECS	Contact for details

Quality Control

Our 3-Amino-4-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF Titration)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.