Description

5-Amino-2-Fluorophenylboronic Acid is a high-value, multifunctional organoboron building block essential for modern synthetic chemistry. Its unique structure, featuring both an amino group and a boronic acid moiety on a fluorinated aromatic ring, makes it a critical intermediate for constructing complex molecules via cross-coupling reactions like the Suzuki-Miyaura reaction. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), especially in the development of fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid partner for forming carbon-carbon bonds, enabling the construction of complex biaryl and heterobiaryl structures in medicinal chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and OFETs, and for creating novel metal-organic frameworks (MOFs) with specific functionalities.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of chemical probes and inhibitors for studying enzyme function and protein-protein interactions.
• Ligand Synthesis: Used to prepare specialized ligands for catalysis, including those for asymmetric synthesis and transition metal complexes.

Basic Information

Product Name	5-Amino-2-Fluorophenylboronic Acid
CAS No.	873566-74-6
Molecular Formula	C6H7BFNO2
Molecular Weight	154.94 g/mol
Synonyms	(5-Amino-2-fluorophenyl)boronic acid; 2-Fluoro-5-aminophenylboronic acid; 5-Amino-2-fluorobenzeneboronic acid; B-(5-Amino-2-fluorophenyl)boronic acid; 2-Fluoro-5-aminobenzene-1-boronic acid; 873566-74-6; 5-Amino-2-fluoro phenyl boronic acid
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability, consistency, and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.