Description

(S)-2-((tert-Butoxycarbonyl)Amino)-3-Methoxy-3-Methylbutanoicacid is a high-purity, non-natural amino acid derivative featuring a chiral center and a tert-butoxycarbonyl (Boc) protecting group. This compound is a critical chiral building block for the synthesis of complex peptides and peptidomimetics, enabling the development of novel pharmaceuticals. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), particularly for metabolic and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used for the solid-phase and solution-phase synthesis of complex peptides, introducing a sterically hindered, methoxy-substituted amino acid residue.
• Protease Inhibitor Development: Serves as a core structural component in the design and synthesis of selective protease inhibitors.
• Chemical Biology Research: Employed in the study of protein-protein interactions and the creation of custom peptide libraries for screening.
• Prodrug Synthesis: Utilized to create prodrug candidates where the Boc-protected amino acid moiety aids in solubility and targeted delivery.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in asymmetric catalytic reactions to construct other enantiomerically pure compounds.

Basic Information

Product Name	(S)-2-((tert-Butoxycarbonyl)Amino)-3-Methoxy-3-Methylbutanoicacid
CAS No.	872689-61-7
Molecular Formula	C11H21NO5
Molecular Weight	247.29 g/mol
Synonyms	Boc-3-Methoxy-3-methyl-D-norvaline; (S)-2-(Boc-Amino)-3-methoxy-3-methylbutanoic acid; Boc-(S)-3-Methoxy-3-methyl-norvaline; (2S)-2-[[(2-Methylpropan-2-yl)oxycarbonyl]amino]-3-methoxy-3-methyl-butanoic acid; (S)-2-((tert-Butoxycarbonyl)amino)-3-methoxy-3-methylbutyric acid; Boc-MeOMeVal-OH; Boc-D-3-Methoxy-3-methyl-norvaline; N-Boc-3-methoxy-3-methyl-D-norvaline
EINECS	Contact for details

Quality Control

Our (S)-2-((tert-Butoxycarbonyl)Amino)-3-Methoxy-3-Methylbutanoicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity compliant with pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.