Description

3-Carboxy-4-Fluorophenylboronic Acid is a high-purity, multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a reactive boronic acid group for Suzuki-Miyaura cross-coupling reactions with a carboxylic acid moiety for further derivatization or salt formation. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing biaryl motifs via Suzuki coupling.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific fluorinated aromatic structures.
• Material Science: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and sensors.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel bidentate ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Carboxy-4-Fluorophenylboronic Acid
CAS No.	872460-12-3
Molecular Formula	C7H6BFO4
Molecular Weight	183.93 g/mol
Synonyms	(3-Carboxy-4-fluorophenyl)boronic acid; 4-Fluoro-3-carboxyphenylboronic acid; 2-Fluoro-5-boronobenzoic acid; 5-Borono-2-fluorobenzoic acid; B-(3-Carboxy-4-fluorophenyl)boronic acid; 3-Borono-4-fluorobenzoic acid; 872460-12-3; 4-Fluoro-3-boronobenzoic acid
EINECS	Contact for details

Quality Control

Our 3-Carboxy-4-Fluorophenylboronic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.