Description

4-Fluoro-3-Methoxycarbonylphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative. This compound is a critical advanced pharmaceutical intermediate and building block in modern organic synthesis, particularly for cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to construct complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, especially those containing fluorinated and ester-functionalized aromatic systems.
• Agrochemical Synthesis: Serves as a building block for creating new herbicides, fungicides, and insecticides with enhanced properties.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular structure is crucial.
• Chemical Biology & Proteomics: Can be used in the synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4-Fluoro-3-Methoxycarbonylphenylboronic Acid Pinacol Ester
CAS No.	872459-87-5
Molecular Formula	C14H18BFO4
Molecular Weight	280.10 g/mol
Synonyms	(4-Fluoro-3-(methoxycarbonyl)phenyl)boronic acid pinacol ester; 2-(4-Fluoro-3-methoxycarbonylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Carbomethoxy-4-fluorophenylboronic acid pinacol ester; Methyl 4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 4-Fluoro-3-methoxycarbonylbenzeneboronic acid pinacol ester; Pinacol (4-Fluoro-3-methoxycarbonylphenyl)boronate
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Methoxycarbonylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.