Description

(5R)-5-Cyclohexyl-2-Pyrrolidinone is a high-purity chiral lactam building block of significant interest in advanced organic synthesis. Its value lies in its rigid, non-planar structure and defined stereochemistry, which are critical for imparting specific three-dimensional properties to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of bioactive molecules, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of stereochemically defined active ingredients for crop protection products.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of chiral ligands used in asymmetric catalysis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals requiring specific spatial orientation.
• Academic & Industrial R&D: A valuable tool for methodological development in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(5R)-5-Cyclohexyl-2-Pyrrolidinone
CAS No.	872358-02-6
Molecular Formula	C10H17NO
Molecular Weight	167.25 g/mol
Synonyms	(R)-5-Cyclohexylpyrrolidin-2-one; (5R)-5-Cyclohexyl-2-pyrrolidinone; (R)-5-Cyclohexyl-2-pyrrolidinone; 2-Pyrrolidinone, 5-cyclohexyl-, (5R)-; (R)-(-)-5-Cyclohexyl-2-pyrrolidinone; (R)-5-Cyclohexyl-dihydro-2(3H)-furanone (tautomer); Chiral Cyclohexyl Lactam
EINECS	Contact for details

Quality Control

Our (5R)-5-Cyclohexyl-2-Pyrrolidinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.