Description

2,4-Difluoro-3-Cyanophenylboronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both electron-withdrawing cyano and fluoro substituents, makes it an indispensable reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily sought after by R&D and process chemistry teams in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging its fluorine atoms to enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing aromatic cores in electronic display and lighting materials, improving performance and durability.
• Polymer & Resin Modification: Incorporated into specialty polymers to impart specific thermal, chemical, or optical properties for high-performance applications.
• Chemical Research & Development: A versatile reagent in academic and industrial labs for exploring new catalytic processes and constructing complex molecular architectures.
• Sensor & Diagnostic Agent Development: Utilized in the synthesis of fluorophore and receptor molecules for biochemical sensing and diagnostic applications.

Basic Information

Product Name	2,4-Difluoro-3-Cyanophenylboronic Acid
CAS No.	871940-31-7
Molecular Formula	C7H4BF2NO2
Molecular Weight	182.92 g/mol
Synonyms	(3-Cyano-2,4-difluorophenyl)boronic acid; 2,4-Difluoro-3-cyanobenzeneboronic acid; 3-Cyano-2,4-difluorophenylboronic acid; Boronic acid, B-(3-cyano-2,4-difluorophenyl)-; 871940-31-7; 2,4-Difluoro-3-cyanophenyl-B(OH)2
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoro-3-Cyanophenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.