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n-[(11Bs)-4,5-Dihydro-3H-Dinaphtho[2,1-C:1',2'-E]Azepin-2-Yl]Trifluoromethanesulfonamide CAS NO 871915-77-4


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CAS No.:871915-77-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-[(11Bs)-4,5-Dihydro-3H-Dinaphtho[2,1-C:1',2'-E]Azepin-2-Yl]Trifluoromethanesulfonamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex polycyclic structure. This compound is of significant value in modern organic synthesis, particularly for constructing sophisticated molecular architectures required in drug discovery. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
  • Organic Synthesis Reagent: Used in advanced organic reactions, including cross-coupling and functional group transformations, due to its reactive trifluoromethanesulfonamide (triflamide) group.
  • Ligand Precursor: Serves as a precursor for chiral ligands or catalysts used in asymmetric synthesis.
  • Material Science Research: Investigated for the development of organic electronic materials or novel polymers with specific optical properties.
  • Academic & Industrial R&D: Employed in research laboratories for methodological studies and the exploration of new chemical entities.

Basic Information

Product Name n-[(11Bs)-4,5-Dihydro-3H-Dinaphtho[2,1-C:1',2'-E]Azepin-2-Yl]Trifluoromethanesulfonamide
CAS No. 871915-77-4
Molecular Formula C24H17F3N2O2S
Molecular Weight 454.47 g/mol
Synonyms 2,3,4,5-Tetrahydro-1H-dinaphtho[2,1-c:1',2'-e]azepin-11b-yl trifluoromethanesulfonamide; (11bS)-2,3,4,5-Tetrahydro-1H-dinaphtho[2,1-c:1',2'-e]azepin-11b-yl triflamide; Trifluoromethanesulfonamide, N-[(11bS)-2,3,4,5-tetrahydro-1H-dinaphtho[2,1-c:1',2'-e]azepin-11b-yl]-; (S)-N-(2,3,4,5-Tetrahydro-1H-dinaphtho[2,1-c:1',2'-e]azepin-11b-yl)trifluoromethanesulfonamide; Dinaphthoazepine Triflamide Derivative
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Quality Control

Our n-[(11Bs)-4,5-Dihydro-3H-Dinaphtho[2,1-C:1',2'-E]Azepin-2-Yl]Trifluoromethanesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity, to ensure it meets the high standards required for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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