Description

Acetamide, n-[(1R)-1-(4-Bromophenyl)Ethyl]-2,2,2-Trifluoro- is a specialized chiral trifluoroacetamide derivative, a high-value intermediate in modern synthetic organic chemistry. Its core value lies in its unique molecular architecture, which combines a brominated aromatic ring with a chiral center and a trifluoroacetamide group, making it a critical building block for the synthesis of complex, biologically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require precise stereochemistry and fluorinated motifs in their development pipelines.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the bromophenyl and trifluoromethyl groups contribute to enhanced biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals or polymers with specific electronic properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags or molecular probes in diagnostic and biochemical research.

Basic Information

Product Name	Acetamide, n-[(1R)-1-(4-Bromophenyl)Ethyl]-2,2,2-Trifluoro-
CAS No.	871720-04-6
Molecular Formula	C10H9BrF3NO
Molecular Weight	296.09 g/mol
Synonyms	N-[(1R)-1-(4-Bromophenyl)ethyl]-2,2,2-trifluoroacetamide; (R)-N-[1-(4-Bromophenyl)ethyl]-2,2,2-trifluoroacetamide; (R)-1-(4-Bromophenyl)ethyl trifluoroacetamide; 2,2,2-Trifluoro-N-[(1R)-1-(4-bromophenyl)ethyl]acetamide; (R)-N-(1-(4-Bromophenyl)ethyl)trifluoroacetamide; (R)-TFA-1-(4-Bromophenyl)ethylamine; (R)-α-Methyl-4-bromobenzylamine trifluoroacetamide
EINECS	Contact for details

Quality Control

Our production of Acetamide, n-[(1R)-1-(4-Bromophenyl)Ethyl]-2,2,2-Trifluoro- adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity, which is critical for downstream synthesis. Each lot is characterized by advanced analytical techniques including HPLC, GC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.