Description

3-Methyl-4-(Trifluoromethyl)Benzonitrile is a high-value, multi-functional aromatic nitrile building block distinguished by its trifluoromethyl and methyl substituents. This compound is critical for introducing lipophilicity and metabolic stability into target molecules, making it a sought-after intermediate in advanced chemical synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a crucial building block for creating novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Used in the synthesis of advanced electronic materials for displays and organic light-emitting diodes (OLEDs), contributing to improved charge transport and stability.
• Functional Polymer Monomer: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, and specific optical properties.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D for constructing complex molecular architectures and as a ligand precursor in catalytic systems.
• Fluorine Chemistry Studies: Acts as a model compound for studying the influence of fluorine atoms on molecular conformation, reactivity, and physicochemical properties.

Basic Information

Product Name	3-Methyl-4-(Trifluoromethyl)Benzonitrile
CAS No.	871571-28-7
Molecular Formula	C9H6F3N
Molecular Weight	185.15 g/mol
Synonyms	4-(Trifluoromethyl)-3-methylbenzonitrile; 3-Methyl-4-trifluoromethylbenzonitrile; 2-Methyl-4-cyanobenzotrifluoride; 4-Cyano-2-methylbenzotrifluoride; 2-Methyl-alpha,alpha,α-trifluoro-p-tolunitrile; 3-Methyl-4-(trifluoromethyl)phenyl cyanide; Benzonitrile, 3-methyl-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 3-Methyl-4-(Trifluoromethyl)Benzonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, NMR, and MS to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.