Description

3-Bromo-2-Fluorobenzamide is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in its bifunctional reactivity, where the bromo and fluoro substituents on the benzamide scaffold allow for selective cross-coupling and further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, serving as a critical intermediate in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Negishi, and Buchwald-Hartwig amination.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for biochemical and pharmacological studies.
• Fine Chemical Production: Intermediate for the manufacture of complex, high-value specialty chemicals used in various industrial applications.

Basic Information

Product Name	3-Bromo-2-Fluorobenzamide
CAS No.	871353-25-2
Molecular Formula	C7H5BrFNO
Molecular Weight	218.03 g/mol
Synonyms	2-Fluoro-3-bromobenzamide; 3-Bromo-2-fluorobenzoic acid amide; Benzamide, 3-bromo-2-fluoro-; 871353-25-2; AI3-52944; AKOS005258565; BRN 2962437; CS-W009767; SCHEMBL1554915; ZINC000257930773
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Fluorobenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.