Description

3-Fluoro-5-(Methylcarbamoyl)Phenylboronic Acid is a high-purity boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functional groups, enabling its use as a versatile coupling partner in cross-coupling reactions, most notably the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who are developing novel active ingredients, particularly for creating complex biaryl and heterobiaryl structures. Its specific substitution pattern makes it a sought-after intermediate for targeted molecular synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing fluorinated biaryl motifs.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a pivotal boronic acid reagent for forming carbon-carbon bonds between aromatic rings, a fundamental step in medicinal chemistry.
• Agrochemical Research: Used in the development and production of advanced herbicides, fungicides, and insecticides requiring specific fluorinated structures.
• Material Science: Intermediate in the synthesis of organic electronic materials, such as ligands for OLEDs and other fluorinated polymers.
• Chemical Synthesis & Process Development: Serves as a versatile reagent in organic synthesis for academic research and industrial-scale process optimization.
• Ligand and Catalyst Preparation: Used to create sophisticated ligands for transition metal catalysts employed in asymmetric synthesis.

Basic Information

Product Name	3-Fluoro-5-(Methylcarbamoyl)Phenylboronic Acid
CAS No.	871332-63-7
Molecular Formula	C9H9BFNO3
Molecular Weight	209.98 g/mol
Synonyms	(3-Fluoro-5-[(methylamino)carbonyl]phenyl)boronic acid; 3-Fluoro-5-(N-methylcarbamoyl)benzeneboronic acid; 5-Borono-3-fluoro-N-methylbenzamide; [3-Fluoro-5-(methylcarbamoyl)phenyl]boronic acid; 3-Fluoro-5-methylcarbamoylphenylboronic acid; Boronic acid, B-[3-fluoro-5-[(methylamino)carbonyl]phenyl]-; CAS 871332-63-7
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Methylcarbamoyl)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory needs. We adhere to cGMP standards where applicable to meet the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.