Description

3-Fluoro-5-Hydroxybenzeneboronic Acid is a multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a boronic acid group and a hydroxyl group on a fluorinated aromatic ring, makes it a versatile intermediate for constructing complex molecules via cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients, advanced materials, and functionalized ligands.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Building block for synthesizing organic electronic materials, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Serves as a ligand for affinity chromatography and in the development of sensors and probes targeting biomolecules.
• Catalyst & Ligand Development: Utilized in the preparation of novel palladium catalysts and bidentate ligands for asymmetric synthesis.
• Polymer Chemistry: Monomer for creating specialty polymers with tailored thermal and chemical resistance properties.

Basic Information

Product Name	3-Fluoro-5-Hydroxybenzeneboronic Acid
CAS No.	871329-82-7
Molecular Formula	C6H6BFO3
Molecular Weight	155.92 g/mol
Synonyms	(3-Fluoro-5-hydroxyphenyl)boronic acid; 3-Fluoro-5-hydroxybenzeneboronic acid pinacol ester (protected form); 5-Borono-3-fluorophenol; 3-Fluoro-5-hydroxy phenylboronic acid; 3-Fluoro-5-hydroxyphenylboronic acid; Boronic acid, B-(3-fluoro-5-hydroxyphenyl)-; 3-Fluoro-5-hydroxybenzeneboronic acid, 95%
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Hydroxybenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.