Description

2-Chloro-3-Fluorophenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. This compound serves as a critical intermediate in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient formation of carbon-carbon bonds. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides requiring specific halogenated aromatic structures.
• Material Science: Serves as a monomer or precursor in the development of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating complex molecular architectures.
• Ligand and Catalyst Preparation: Used to synthesize specialized ligands for transition metal catalysis and other advanced catalytic systems.
• Fine Chemical Production: Employed in the custom synthesis of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	2-Chloro-3-Fluorophenylboronic Acid
CAS No.	871329-52-1
Molecular Formula	C6H5BClFO2
Molecular Weight	173.37 g/mol
Synonyms	(2-Chloro-3-fluorophenyl)boronic acid; 2-Chloro-3-fluorobenzeneboronic acid; Boronic acid, B-(2-chloro-3-fluorophenyl)-; 2-Chloro-3-fluoro phenylboronic acid; 2-Cl-3-F-PhB(OH)2; 871329-52-1; B-(2-Chloro-3-fluorophenyl)boronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-Fluorophenylboronic Acid is manufactured and tested under strict quality management systems to ensure consistent purity and performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' needs for reliable and traceable raw materials in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	Conforms
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.