Description

2-(Boc-Amino)-3-Methylbutylamine is a protected amino acid derivative featuring a tert-butoxycarbonyl (Boc) group, a crucial intermediate in modern organic synthesis. Its primary value lies in providing a versatile, orthogonal protecting group strategy for amines, enabling complex multi-step reactions in peptide and small molecule synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical industries who require high-purity building blocks for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly in peptide-based therapeutics.
• Peptide Synthesis: Used extensively in solid-phase and solution-phase peptide synthesis (SPPS) for the controlled introduction of valine or other branched-chain amino acid analogs.
• Protecting Group Chemistry: Serves as a reagent for introducing the acid-labile Boc protecting group onto amine functionalities in complex molecular architectures.
• Bioconjugation: Employed in the development of antibody-drug conjugates (ADCs) and other bioconjugates where a stable, cleavable linker is required.
• Agrochemical Research: Acts as a synthetic precursor for developing novel pesticides and herbicides with specific bioactive properties.
• Chemical Biology Probes: Utilized in the creation of labeled probes and molecular tools for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	2-(Boc-Amino)-3-Methylbutylamine
CAS No.	871235-24-4
Molecular Formula	C10H22N2O2
Molecular Weight	202.30 g/mol
Synonyms	N-Boc-1,2-Diamino-3-methylbutane; tert-Butyl (1-Amino-3-methylbutan-2-yl)carbamate; 2-((tert-Butoxycarbonyl)amino)-3-methylbutan-1-amine; Boc-Dab(Me)-OH; (2-Amino-3-methylbutyl)carbamic acid tert-butyl ester; Nα-Boc-2,3-diaminobutanoic acid derivative; 1,2-Diamino-3-methylbutane, N-Boc protected.
EINECS	Contact for details

Quality Control

Our 2-(Boc-Amino)-3-Methylbutylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C or as specified on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.