Description

Potassium 2,6-Dimethoxyphenyltrifluoroborate is a versatile and highly reactive organoboron reagent, specifically an aryltrifluoroborate salt. This compound is valued for its enhanced stability and solubility in aqueous and organic media compared to traditional boronic acids, making it a superior choice for critical cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and this potassium trifluoroborate, essential for synthesizing biaryl structures in drug discovery.
• Pharmaceutical Intermediate Synthesis: Used in the production of active pharmaceutical ingredients (APIs) and complex organic molecules requiring the 2,6-dimethoxyphenyl moiety.
• Agrochemical Development: Employed in the research and synthesis of novel herbicides, fungicides, and insecticides where specific aryl groups are needed.
• Material Science Research: Serves as a building block for creating organic electronic materials, ligands for catalysts, and specialty polymers.
• Process Chemistry & Scale-up: Its improved handling characteristics make it suitable for optimizing and scaling laboratory synthesis to pilot and manufacturing scales.
• Chemical Biology & Probe Development: Useful for bioconjugation and labeling applications due to its selective reactivity under mild conditions.

Basic Information

Product Name	Potassium 2,6-Dimethoxyphenyltrifluoroborate
CAS No.	871231-42-4
Molecular Formula	C8H9BF3KO2
Molecular Weight	244.06 g/mol
Synonyms	Potassium (2,6-Dimethoxyphenyl)trifluoroborate; 2,6-Dimethoxyphenyltrifluoroborate Potassium Salt; (2,6-Dimethoxyphenyl)trifluoroboronic Acid Potassium Salt; Potassium 2,6-Dimethoxybenzenetrifluoroborate; 2,6-Dimethoxybenzenetrifluoroboronic Acid Potassium Salt; Potassium 2,6-Dimethoxyphenyl-BF3; 871231-42-4; Potassium (2,6-Dimethoxy)phenyltrifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium 2,6-Dimethoxyphenyltrifluoroborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay (NMR), purity (HPLC), and moisture content (KF). Our quality system is designed to meet the stringent requirements of research and development as well as cGMP environments for non-GMP intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility Test	Soluble in water, methanol, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.