Description

(R)-Vapol Hydrogenphosphate is a chiral organocatalyst and ligand, specifically the hydrogenphosphate salt of the (R)-VAPOL phosphoric acid derivative. This compound is valued for its high enantioselectivity and efficiency in facilitating a wide range of asymmetric organic transformations. It is a critical reagent for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to synthesize single-enantiomer compounds.

Application

• As a chiral Brønsted acid catalyst in enantioselective synthesis.
• As a ligand for metal-catalyzed asymmetric reactions.
• Key reagent in the synthesis of active pharmaceutical ingredients (APIs) and drug intermediates.
• Used in the development of agrochemicals and specialty fine chemicals requiring high optical purity.
• Facilitates asymmetric Mannich, Friedel-Crafts, and transfer hydrogenation reactions.
• Applied in academic and industrial research for methodological development in organic chemistry.

Basic Information

Product Name	(R)-Vapol Hydrogenphosphate
CAS No.	871130-18-6
Molecular Formula	C26H20O4P2
Molecular Weight	458.38 g/mol
Synonyms	(R)-VAPOL Hydrogenphosphate; (R)-2,2'-Diphenyl-[3,3'-biphenanthrene]-4,4'-diyl hydrogenphosphate; (R)-VAPOL Phosphate; (R)-VAPOL Phosphoric Acid; (R)-VAPOL-HPO4; VAPOL hydrogen phosphate (R)-form; (R)-VAPOL Dihydrogen Phosphate; (11bR)-4,4'-(Hydrogenphosphate)dibenzo[a,c]phenanthridine
EINECS	Contact for details

Quality Control

Our (R)-Vapol Hydrogenphosphate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity (HPLC) and chemical identity confirmation (NMR, IR), to ensure it meets the high standards required for asymmetric synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee reproducible performance and reliable results in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.