Description

6-(3,5-Difluorophenyl)-6-Oxohexanoic Acid is a high-purity organic intermediate featuring a difluorophenyl ketone moiety attached to a hexanoic acid chain. This compound is valued for its role as a critical building block in the synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and fungicides, where the difluorophenyl group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for specialty polymers with unique thermal or optical properties.
• Bioconjugation Chemistry: The carboxylic acid functionality allows for coupling reactions, useful in probe and linker molecule synthesis for biochemical applications.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	6-(3,5-Difluorophenyl)-6-Oxohexanoic Acid
CAS No.	871127-79-6
Molecular Formula	C12H12F2O3
Molecular Weight	242.22 g/mol
Synonyms	6-Oxo-6-(3,5-difluorophenyl)hexanoic acid; 3,5-Difluoro-ω-oxobenzenehexanoic acid; 6-(3,5-Difluorobenzoyl)hexanoic acid; Hexanoic acid, 6-(3,5-difluorophenyl)-6-oxo-; 871127-79-6; 6-(3,5-Difluorophenyl)-6-oxo-hexanoic acid; ω-Oxo-3,5-difluorobenzenehexanoic acid
EINECS	Contact for details

Quality Control

Every batch of 6-(3,5-Difluorophenyl)-6-Oxohexanoic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with detailed impurity profiling available. Certificates of Analysis (COA) documenting lot-specific results are provided with each shipment, and custom purity grades or analytical packages can be developed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is stable under inert atmosphere but should be kept away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.