Description

4-(2,5-Difluorophenyl)-4-Oxobutanoic Acid is a high-purity fluorinated organic intermediate of significant importance in advanced chemical synthesis. This compound matters for its role as a versatile building block in the development of complex, value-added molecules, particularly within the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, where its difluorophenyl and oxobutanoic acid moieties offer critical structural and electronic properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of modern herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of novel fluorinated polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule construction and scale-up projects.

Basic Information

Product Name	4-(2,5-Difluorophenyl)-4-Oxobutanoic Acid
CAS No.	871127-78-5
Molecular Formula	C10H6F2O3
Molecular Weight	212.15 g/mol
Synonyms	4-Oxo-4-(2,5-difluorophenyl)butanoic acid; 2,5-Difluoro-γ-oxobenzenebutanoic acid; γ-Oxo-2,5-difluorobenzenebutanoic acid; 4-(2,5-Difluorobenzoyl)butyric acid; Butanoic acid, 4-(2,5-difluorophenyl)-4-oxo-; 871127-78-5; 4-(2,5-Difluorophenyl)-4-oxobutyric acid
EINECS	Contact for details

Quality Control

Every batch of 4-(2,5-Difluorophenyl)-4-Oxobutanoic Acid is produced and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency, which is critical for your synthetic processes. Our standard quality commitment includes comprehensive analysis via HPLC, NMR, and MS to confirm identity and purity. A Certificate of Analysis (COA) detailing all relevant specifications is provided with each shipment to ensure full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.