Description

4-Isopropoxy-2,3,5,6-Tetrafluorobenzeneboronic Acid CAS NO 871126-28-2 is a highly functionalized organoboron compound, serving as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a perfluorinated aromatic ring and an isopropoxy substituent, which imparts unique electronic properties and solubility profiles. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex molecules where fluorination is required to modulate bioactivity, metabolic stability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides where the fluorine atoms enhance compound stability, bioavailability, and environmental persistence.
• Material Science: Building block for synthesizing specialty polymers, liquid crystals, and organic electronic materials that benefit from fluorinated aromatic systems.
• Suzuki-Miyaura Cross-Coupling: A versatile reagent for forming carbon-carbon bonds to construct biaryl structures, a common motif in many functional materials and bioactive compounds.
• Chemical Research & Development: A valuable tool for medicinal chemists and process chemists exploring structure-activity relationships (SAR) and developing new synthetic routes.
• Fluorinated Liquid Crystal Precursor: Used in the development of advanced display materials due to the influence of fluorine on molecular alignment and physical properties.

Basic Information

Product Name	4-Isopropoxy-2,3,5,6-Tetrafluorobenzeneboronic Acid
CAS No.	871126-28-2
Molecular Formula	C9H9BF4O3
Molecular Weight	244.0 g/mol
Synonyms	2,3,5,6-Tetrafluoro-4-isopropoxybenzeneboronic Acid; (4-Isopropoxy-2,3,5,6-tetrafluorophenyl)boronic Acid; B-(4-Isopropoxy-2,3,5,6-tetrafluorophenyl)boronic Acid; 4-Isopropoxy-2,3,5,6-Tetrafluorophenylboronic Acid; 871126-28-2; Tetrafluoroisopropoxybenzeneboronic Acid
EINECS	Contact for details

Quality Control

Our 4-Isopropoxy-2,3,5,6-Tetrafluorobenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain integrity and batch-to-batch consistency supports your development and production timelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.