Description

2-(3'-Fluorobenzyloxy)Phenylboronic Acid is a high-purity, functionalized boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing novel active ingredients and organic electronic components.

Application

• Pharmaceutical Intermediate: A key synthon for constructing biaryl structures found in active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific fluorinated aromatic motifs.
• Material Science Research: Serves as a monomer or precursor in the development of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Utilized in the synthesis of probes and inhibitors that target enzymes or biological pathways, leveraging boronic acid's affinity for diols.
• Catalyst Ligand Development: Acts as a precursor for sophisticated ligands used in homogeneous catalysis to control reaction selectivity and efficiency.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-(3'-Fluorobenzyloxy)Phenylboronic Acid
CAS No.	871126-24-8
Molecular Formula	C₁₃H₁₂BFO₃
Molecular Weight	246.05 g/mol
Synonyms	[2-(3-Fluorobenzyloxy)phenyl]boronic acid; (2-((3-Fluorobenzyl)oxy)phenyl)boronic acid; 2-[(3-Fluorophenyl)methoxy]benzeneboronic acid; B-[2-[(3-Fluorophenyl)methoxy]phenyl]boronic acid; 2-(3-Fluorobenzyloxy)benzeneboronic Acid; 871126-24-8; 2-(3-Fluorobenzyloxy)phenylboronic acid pinacol ester (common derivative)
EINECS	Contact for details

Quality Control

Our 2-(3'-Fluorobenzyloxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.