Description

3-Butoxy-2,4,6-Trifluorophenylboronic Acid is a high-purity organoboron compound, specifically a substituted phenylboronic acid, serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex fluorinated aromatic systems.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the trifluorophenyl moiety enhances biological activity and stability.
• Material Science Research: Building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where fluorination tunes electronic properties.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors that leverage boronic acid-diol interactions for detection.
• Custom Synthesis and Contract Manufacturing: A vital reagent for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Item	Detail
Product Name	3-Butoxy-2,4,6-Trifluorophenylboronic Acid
CAS No.	871126-23-7
Molecular Formula	C₁₀H₁₁BF₃O₃
Molecular Weight	238.00 g/mol
Synonyms	2,4,6-Trifluoro-3-butoxybenzeneboronic Acid; (3-Butoxy-2,4,6-trifluorophenyl)boronic Acid; B-(3-Butoxy-2,4,6-trifluorophenyl)boronic Acid; 3-n-Butoxy-2,4,6-trifluorophenylboronic Acid; 871126-23-7; Boronic acid, B-(3-butoxy-2,4,6-trifluorophenyl)-; 3-Butoxy-2,4,6-trifluorobenzeneboronic Acid
EINECS	Contact for details

Quality Control

Our 3-Butoxy-2,4,6-Trifluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay (NMR)	≥95.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.