Description

3-Fluoro-2-Formylphenylboronic Acid is a multifunctional boronic acid derivative that serves as a key synthetic intermediate in modern organic chemistry. Its value lies in the strategic combination of a formyl group and a boronic acid moiety on a fluorinated aromatic ring, enabling sequential cross-coupling and condensation reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of complex drug candidates, particularly in Suzuki-Miyaura cross-coupling reactions to create biaryl structures.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Precursor: Employed in the development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) and monomers for conjugated polymers.
• Chemical Biology Probes: Serves as a starting material for creating fluorescent sensors and bioconjugation reagents that target specific biomolecules.
• Catalyst and Ligand Development: The functional groups allow for its use in designing novel catalysts and chiral ligands for asymmetric synthesis.
• Academic and R&D: A valuable reagent for methodological studies in organic synthesis and exploring new reaction pathways in university and corporate laboratories.

Basic Information

Product Name	3-Fluoro-2-Formylphenylboronic Acid
CAS No.	871126-15-7
Molecular Formula	C7H6BFO3
Molecular Weight	167.93 g/mol
Synonyms	(3-Fluoro-2-formylphenyl)boronic acid; 2-Formyl-3-fluorobenzeneboronic acid; 3-Fluoro-2-formylbenzeneboronic acid; 3-Fluoro-2-carboxybenzaldehyde boronic acid (tautomer); Boronic acid, B-(3-fluoro-2-formylphenyl)-; 3-Fluoro-2-formylphenyl-B(OH)2; 2-Carboxy-3-fluorophenylboronic acid (tautomeric form)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Formylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.