Description

6-Bromo-3-Ethoxy-2-Fluorobenzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its unique halogenated and alkoxy-substituted aromatic structure, which enables precise cross-coupling reactions essential for constructing complex molecules. This compound is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection agents, leveraging its halogen and fluorine substituents for bioactivity.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its conjugated aromatic system.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-scale API development.

Basic Information

Item	Details
Product Name	6-Bromo-3-Ethoxy-2-Fluorobenzeneboronic Acid
CAS No.	871126-14-6
Molecular Formula	C8H9BBrFO3
Molecular Weight	262.87 g/mol
Synonyms	2-Fluoro-6-bromo-3-ethoxybenzeneboronic acid; (6-Bromo-3-ethoxy-2-fluorophenyl)boronic acid; 6-Bromo-3-ethoxy-2-fluorophenylboronic acid; Boronic acid, B-(6-bromo-3-ethoxy-2-fluorophenyl)-; 871126-14-6; AKOS005258509
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Ethoxy-2-Fluorobenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.