Description

2 6-Difluoro-4-Formylphenylboronic Acid is a high-value, multi-functional boronic acid derivative characterized by its reactive formyl and boronic acid groups on a difluorinated aromatic ring. This compound matters as a critical building block in modern synthetic chemistry, enabling the precise construction of complex molecules through Suzuki-Miyaura cross-coupling and other boronic acid-mediated reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated biaryl structures found in active pharmaceutical ingredients (APIs), leveraging the Suzuki-Miyaura cross-coupling reaction.
• Agrochemical Synthesis: Used in the research and development of novel, fluorinated pesticides and herbicides, where the difluoro and formyl groups impart specific biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated ligands and organocatalysts used in asymmetric synthesis and material science.
• Functional Material Precursor: Employed in the synthesis of organic electronic materials, such as OLEDs and OFETs, where fluorination tunes electronic properties and stability.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors that target specific biological pathways.
• Custom Synthesis and Contract Research: A valuable reagent for CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2,6-Difluoro-4-Formylphenylboronic Acid
CAS No.	871125-93-8
Molecular Formula	C7H5BF2O3
Molecular Weight	185.92 g/mol
Synonyms	(4-Formyl-2,6-difluorophenyl)boronic acid; 2,6-Difluoro-4-formylbenzeneboronic acid; 4-Borono-2,6-difluorobenzaldehyde; 2,6-Difluoro-4-carboxaldehydephenylboronic acid; 2,6-Difluoro-4-formylphenyl-B(OH)2; DFFPBA; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-4-Formylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.