Description

2-(3-Bromo-5-Methylphenyl)Acetonitrile is a versatile brominated aromatic nitrile building block, essential for advanced organic synthesis. Its molecular structure, featuring both a reactive nitrile group and a bromine substituent on a methylphenyl ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzyl nitrile moiety.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the bromine atom allows for further functionalization.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings.
• Material Science Research: Acts as a monomer or building block for developing advanced polymers, liquid crystals, or organic electronic materials.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems and drug-target interactions.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-(3-Bromo-5-Methylphenyl)Acetonitrile
CAS No.	871116-91-5
Molecular Formula	C9H8BrN
Molecular Weight	210.07 g/mol
Synonyms	(3-Bromo-5-methylphenyl)acetonitrile; 2-(3-Bromo-5-methylphenyl)ethanenitrile; m-Bromo-m-methylbenzyl cyanide; 3'-Bromo-5'-methylphenylacetonitrile; 1-Bromo-3-(cyanomethyl)-5-methylbenzene; α-(3-Bromo-5-methylphenyl)acetonitrile; 3-Bromo-5-methylbenzyl cyanide
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Bromo-5-Methylphenyl)Acetonitrile is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.