Description

4-Bromo-2,5-Difluorophenylacetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its unique halogenated and fluorinated structure, which enables precise molecular modifications in complex chemical architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging the fluorine and bromine substituents for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a sophisticated building block for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of advanced organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs), where fluorinated aromatics are critical.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex fluorinated intermediates.
• Academic and Industrial R&D: Utilized in exploratory chemistry for constructing novel chemical entities in medicinal chemistry and chemical biology programs.

Basic Information

Product Name	4-Bromo-2,5-Difluorophenylacetic Acid
CAS No.	871035-64-2
Molecular Formula	C8H5BrF2O2
Molecular Weight	251.03 g/mol
Synonyms	2-(4-Bromo-2,5-difluorophenyl)acetic Acid; (4-Bromo-2,5-difluorophenyl)acetic Acid; 4-Bromo-2,5-difluorobenzeneacetic Acid; α-(4-Bromo-2,5-difluorophenyl)acetic Acid; 871035-64-2; 4-Br-2,5-F2-PhAA; BDfPAA
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2,5-Difluorophenylacetic Acid adheres to stringent in-process controls and final batch release testing to ensure consistent high purity and reliable performance. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system supports compliance with cGMP and ISO standards for traceability and documentation, making this material suitable for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.