Description

[5-Chloro-2-(Trifluoromethoxy)Phenyl]Boronic Acid is a high-purity organoboron compound serving as a critical building block in modern synthetic chemistry. Its value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This boronic acid is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex biaryl structures.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific halogenated and fluorinated motifs.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its structural features can tune electronic properties.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of molecular probes and inhibitors.
• Catalyst & Ligand Development: Serves as a starting material for synthesizing novel palladium catalyst ligands and other organometallic complexes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-molecule libraries for client projects.

Basic Information

Product Name	[5-Chloro-2-(Trifluoromethoxy)Phenyl]Boronic Acid
CAS No.	870822-78-9
Molecular Formula	C7H5BClF3O3
Molecular Weight	239.38 g/mol
Synonyms	(5-Chloro-2-(trifluoromethoxy)phenyl)boronic acid; 5-Chloro-2-(trifluoromethoxy)benzeneboronic acid; 2-Chloro-5-(trifluoromethoxy)phenylboronic acid; Boronic acid, B-[5-chloro-2-(trifluoromethoxy)phenyl]-; [5-Chloro-2-(trifluoromethoxy)phenyl]boronic acid; 870822-78-9; 5-Chloro-2-trifluoromethoxyphenylboronic acid
EINECS	Contact for details

Quality Control

Our [5-Chloro-2-(Trifluoromethoxy)Phenyl]Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.