Description

2,6-Difluoro-3-Methoxybenzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, particularly for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex difluorinated biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific fluorine-substituted aromatic systems.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for OLEDs and semiconductors, where fluorine substitution tunes electronic properties.
• Cross-Coupling Reactions: Serves as a versatile boronic acid partner in palladium-catalyzed Suzuki-Miyaura reactions for carbon-carbon bond formation.
• Chemical Biology & Probe Development: Useful for creating fluorescent tags, molecular probes, and other tools for biological research and diagnostics.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up processes.

Basic Information

Product Name	2,6-Difluoro-3-Methoxybenzeneboronic Acid
CAS No.	870779-02-5
Molecular Formula	C7H7BF2O3
Molecular Weight	187.94 g/mol
Synonyms	(2,6-Difluoro-3-methoxyphenyl)boronic acid; 3-Methoxy-2,6-difluorobenzeneboronic acid; 2,6-Difluoro-3-methoxybenzeneboronic acid pinacol ester (common derivative); B-(2,6-Difluoro-3-methoxyphenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Methoxybenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring traceability and consistency, from research to commercial-scale synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.