Description

2-(4-Fluorobenzyloxy)Phenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for forming carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to synthesize complex molecules and advanced intermediates. The product is supplied with a CAS number of 870779-01-4.

Application

This versatile boronic acid ester is a key reagent in several high-value industrial and research applications:

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in areas requiring fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that benefit from the stability and reactivity of the boronic acid functional group.
• Material Science Research: Serves as a monomer or precursor in the creation of organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and inhibitors for studying enzyme function and protein interactions.
• Ligand Synthesis for Catalysis: Used to prepare sophisticated ligands for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom chemical synthesis services targeting complex, multi-step organic molecules.

Basic Information

Product Name	2-(4-Fluorobenzyloxy)Phenylboronic Acid
CAS No.	870779-01-4
Molecular Formula	C13H12BFO3
Molecular Weight	246.05 g/mol
Synonyms	[2-(4-Fluorobenzyloxy)phenyl]boronic acid; (2-((4-Fluorobenzyl)oxy)phenyl)boronic acid; 2-(4-Fluorobenzyloxy)benzeneboronic acid; B-[2-[(4-Fluorophenyl)methoxy]phenyl]boronic acid; 870779-01-4; 2-(p-Fluorobenzyloxy)phenylboronic acid
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorobenzyloxy)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance in coupling reactions. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting identity, purity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.