Description

2,4-Dibromo-6-Fluorophenylboronic Acid is a high-value organoboron building block, specifically a halogenated phenylboronic acid derivative. Its core value proposition lies in enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures in advanced chemical synthesis. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require a reliable, high-purity reagent for introducing a functionalized aromatic ring system.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates containing complex halogenated biphenyl or heterocyclic motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where specific halogen substitution patterns are required for bioactivity.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands for transition metal catalysts used in asymmetric synthesis.
• Organic Electronic Materials: Employed in the synthesis of conjugated polymers and small molecules for applications in OLEDs, OFETs, and other optoelectronic devices.
• Chemical Biology Probes: Useful for constructing molecular probes and tags due to the orthogonal reactivity of the boronic acid group and the stability of the halogen substituents.
• Custom Synthesis and Contract Research: A critical reagent for custom synthesis organizations (CSOs) and R&D laboratories working on proprietary chemical entities.

Basic Information

Item	Detail
Product Name	2,4-Dibromo-6-Fluorophenylboronic Acid
CAS No.	870778-96-4
Molecular Formula	C6H4BBr2FO2
Molecular Weight	297.71 g/mol
Synonyms	(2,4-Dibromo-6-fluorophenyl)boronic acid; 2,4-Dibromo-6-fluorobenzeneboronic acid; B-(2,4-Dibromo-6-fluorophenyl)boronic acid; 870778-96-4; 2,4-Dibromo-6-fluoro phenyl boronic acid; 6-Fluoro-2,4-dibromophenylboronic acid
EINECS	Contact for details

Quality Control

Our 2,4-Dibromo-6-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening a new container to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.